Quantitative analysis of the viral and proviral form of Feline Immunodeficiency Virus (FIV) in cats or other felines (tiger, lion, panther, etc.).
Test indications
- Symptomatic animals:
- Diagnosis of a IVF infection causing clinical signs varied (anemia, immunosuppression, recurrent infections, etc.).
- Control of animals detected positive by immunological tests.
- Monitoring of viral and/or proviral blood load (contact us).
- Asymptomatic animals:
- Early phase of infection (recent contact)
- Young kittens born to infected mothers or with positive serology
- Confirmation of a positive immunological test result (performed in the clinic or laboratory)
- Whatever the clinical status of the animal: Confirmation of questionable immunological tests.
Test characteristics
- Real-time RT-PCR: Quantitative amplification of viral RNA and DNA. Detection of provirus (virus genome integrated into the cat genome, essential in the replication cycle of retroviruses) and the free virus genome (translates viral replication).
- Detection threshold
- Analyse quantitative on plasma or serum for viral load monitoring (contact us).
Samples to be taken
- Song (EDTA)
- Blood (EDTA) and oropharyngeal cells (cytobrush or dry swab) in case of oral symptoms (stomatitis, gingivitis, etc.)
- Bone marrow (EDTA)
- CSF or aqueous humor for nervous/ocular forms (uveitis) (and possibly blood on EDTA)
- Tumor tissue, organs, lymph nodes, effusions, pad biopsy… (not fixed)
Interpretation of the result
- Negative result: Absence of FIV infection or viral load in the sample below the detection threshold of the test. Allows the etiology to be excluded in a symptomatic animal.
- Positive result : The animal is infected with FIV. The viral load is correlated with clinical signs, so it is possible to follow the progression of the disease in a seropositive cat.
Do not hesitate to Contact Us for an interpretation of the quantitative result